INT158684

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Context Info
Confidence 0.51
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAPK8, BCL2L11) mitochondrion (MAPK8, BCL2L11) cytoplasm (MAPK8, BCL2L11)
nucleoplasm (MAPK8) plasma membrane (BCL2L11) nucleus (MAPK8)
MAPK8 (Homo sapiens)
BCL2L11 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 10 99.36 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 4 82.24 Quite High
Death 2 74.80 Quite High
Cancer 1 70.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ROS-amplified JNK induced cytochrome c release and caspase-9/3 activation through enhancement of expression of the proapoptotic protein Bim and reduction of expression of the antiapoptotic protein Bcl-2.
JNK Positive_regulation (enhancement) of Gene_expression (expression) of Bim
1) Confidence 0.51 Published 2009 Journal FEBS J. Section Abstract Doc Link 19292871 Disease Relevance 0.44 Pain Relevance 0.78

General Comments

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