INT158685

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK8) cell differentiation (ROS1) mitochondrion (MAPK8)
response to stress (MAPK8) cytoplasm (MAPK8) cell proliferation (ROS1)
ROS1 (Homo sapiens)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 10 94.04 High High
Disease Link Frequency Relevance Heat
Apoptosis 4 89.40 High High
Death 2 84.00 Quite High
Cancer 1 79.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ROS in turn exerted feedback regulation on JNK activation, as shown by the observations that cyclosporin A and the antioxidant N-acetylcysteine significantly inhibited the phosphorylation of JNK induced by morphine.
ROS Regulation (regulation) of Positive_regulation (activation) of JNK associated with morphine
1) Confidence 0.21 Published 2009 Journal FEBS J. Section Abstract Doc Link 19292871 Disease Relevance 0.39 Pain Relevance 0.64

General Comments

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