INT158690

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.07
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.77
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

3.8-1.4 (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 3 81.52 Quite High
peripheral neuropathy 2 45.28 Quite Low
Disease Link Frequency Relevance Heat
Variegate Porphyria 1 99.96 Very High Very High Very High
Hepatic Porphyrias 11 99.72 Very High Very High Very High
Porphyria 44 98.24 Very High Very High Very High
Hereditary Coproporphyria 1 96.72 Very High Very High Very High
Syndrome 3 86.76 High High
Disease 55 84.84 Quite High
Abdominal Pain 3 81.52 Quite High
Neurodegenerative Disease 3 70.88 Quite High
Anxiety Disorder 2 64.56 Quite High
Sleep Disorders 1 63.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acute intermittent porphyria is an autosomal dominantly inherited disorder, classified as acute hepatic porphyria, caused by a deficiency of hydroxymethylbilane synthase (EC 2.5.1.61, EC 4.3.1.8, also known as porphobilinogen deaminase, uroporphyrinogen I synthase), the third enzyme in heme biosynthesis.
Negative_regulation (deficiency) of EC 4.3.1.8 associated with porphyria and hepatic porphyrias
1) Confidence 0.07 Published 2009 Journal FEBS J. Section Abstract Doc Link 19292878 Disease Relevance 0.59 Pain Relevance 0.08
coproporphyrinogen oxidase, EC 1.3.3.3), and variegate porphyria

(deficiency of protoporphyrinogen oxidase, EC 1.3.3.4).

Negative_regulation (deficiency) of EC 1.3.3.4 associated with variegate porphyria
2) Confidence 0.01 Published 2006 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC1559910 Disease Relevance 2.18 Pain Relevance 0.05

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox