INT158772

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 1.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ptges) cytoplasm (Ptges)
Ptges (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tolerance 9 100.00 Very High Very High Very High
Morphine 9 100.00 Very High Very High Very High
Calcitonin gene-related peptide 7 97.56 Very High Very High Very High
Antinociceptive 1 91.32 High High
Spinal cord 1 88.44 High High
analgesia 4 76.08 Quite High
Pain 1 67.52 Quite High
Disease Link Frequency Relevance Heat
Pain 1 67.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, the inhibition of the ERK pathway suppressed the development of tolerance and morphine-induced up-regulation of IL-1beta, TNF-alpha, and mPGES-1.
Negative_regulation (suppressed) of Regulation (regulation) of mPGES-1 associated with tolerance and morphine
1) Confidence 0.03 Published 2009 Journal FASEB J. Section Abstract Doc Link 19299480 Disease Relevance 0.07 Pain Relevance 1.81

General Comments

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