INT158796

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.70
First Reported 2005
Last Reported 2010
Negated 3
Speculated 0
Reported most in Body
Documents 67
Total Number 68
Disease Relevance 38.97
Pain Relevance 8.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SMUG1) hydrolase activity, acting on glycosyl bonds (SMUG1) nucleolus (SMUG1)
nucleus (SMUG1) DNA binding (SMUG1)
Anatomy Link Frequency
uterine horns 3
leukocytes 3
brain 2
right uterine horns 2
left uterine horn 2
SMUG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 198 99.98 Very High Very High Very High
positron emission tomography 1045 99.76 Very High Very High Very High
corticosteroid 24 99.64 Very High Very High Very High
medulla 108 98.44 Very High Very High Very High
imagery 1305 97.64 Very High Very High Very High
fibrosis 51 96.80 Very High Very High Very High
Thalamus 32 95.72 Very High Very High Very High
Anterior cingulate cortex 8 95.32 Very High Very High Very High
anesthesia 70 94.92 High High
ischemia 36 94.72 High High
Disease Link Frequency Relevance Heat
Dyskinesias 186 100.00 Very High Very High Very High
Epilepsy 118 100.00 Very High Very High Very High
Cancer 1670 99.98 Very High Very High Very High
INFLAMMATION 203 99.98 Very High Very High Very High
Atherosclerosis 132 99.84 Very High Very High Very High
Malignant Neoplastic Disease 285 99.74 Very High Very High Very High
Hypoxia 49 99.64 Very High Very High Very High
Hodgkin's Disease 12 99.62 Very High Very High Very High
Breast Cancer 152 99.52 Very High Very High Very High
Lymphatic System Cancer 101 99.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The images revealed peripherally increased FDG activity in the left lower lung mass.
Positive_regulation (increased) of FDG in lung
1) Confidence 0.70 Published 2009 Journal Clin Nucl Med Section Abstract Doc Link 19300056 Disease Relevance 0.58 Pain Relevance 0.13
It is also challenging to differentiate lesions due to malignancy from lesions due to inflammation in which FDG accumulation is equally intense due to increased glucose metabolic rates.
Positive_regulation (accumulation) of FDG associated with malignant neoplastic disease and inflammation
2) Confidence 0.58 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.69 Pain Relevance 0.14
Stromal tumors of the gastrointestinal tract may show heterogeneity in FDG accumulation between different lesions of the same patient.
Positive_regulation (accumulation) of FDG associated with cancer
3) Confidence 0.58 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.96 Pain Relevance 0.14
Malignant lesions often accumulate FDG but cannot be detected by CT.
Positive_regulation (accumulate) of FDG associated with malignant neoplastic disease
4) Confidence 0.58 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.93 Pain Relevance 0.19
Multiple metastases to the lymph nodes and muscle had an increased uptake in FDG-PET, and the increased uptake may be representative of epithelioid sarcoma.
Positive_regulation (increased) of FDG-PET in muscle associated with sarcoma and metastasis
5) Confidence 0.44 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2527488 Disease Relevance 1.36 Pain Relevance 0
Computed tomography showed soft tissue masses surrounding the left iliac artery and in the bilateral pulmonary hilum, and the first FDG PET showed increased FDG uptake by the lesions.
Positive_regulation (increased) of FDG in iliac artery
6) Confidence 0.44 Published 2010 Journal Ann Nucl Med Section Abstract Doc Link 20112003 Disease Relevance 0.52 Pain Relevance 0.49
The third FDG PET after cessation of corticosteroid treatment showed increased FDG uptake in the mediastinum, and so Sairei-to treatment was initiated.
Positive_regulation (increased) of FDG associated with corticosteroid
7) Confidence 0.44 Published 2010 Journal Ann Nucl Med Section Abstract Doc Link 20112003 Disease Relevance 0.50 Pain Relevance 0.61
The PET images showed diffuse moderately increased FDG uptake in the periostea of the long bones of the legs, with some focal sites of more intense FDG uptake in the thicker portions of the periosteum.
Positive_regulation (increased) of FDG in legs
8) Confidence 0.44 Published 2009 Journal Clin Nucl Med Section Abstract Doc Link 19692831 Disease Relevance 0.50 Pain Relevance 0.13
Consequently, an increase in patient throughput and a simultaneous decrease in FDG requirements for the same number of patients may bring additional income to the institution.
Positive_regulation (requirements) of FDG
9) Confidence 0.42 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.16 Pain Relevance 0.06
PET/CT may detect and localize successfully the malignant lesion with increased FDG uptake.


Positive_regulation (increased) of FDG associated with malignant neoplastic disease
10) Confidence 0.42 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 1.04 Pain Relevance 0.18
Even with fewer FDG requirements, a better price for the radiopharmaceutical is negotiable, as the examination sequence gets faster [1,11,93,96].
Positive_regulation (requirements) of FDG
11) Confidence 0.42 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.06 Pain Relevance 0.06
Despite increased FDG uptake for breast cancer and metastatic lymph nodes, pulmonary nodules and masses had no FDG uptake so we excluded malignancy by FDG-PET scan and decided with a high degree of certainty that they were benign lesions.
Positive_regulation (increased) of FDG in nodules associated with malignant neoplastic disease and breast cancer
12) Confidence 0.42 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2257945 Disease Relevance 1.45 Pain Relevance 0
Both Hodgkin and non-Hodgkin lymphoma usually show high FDG accumulation.
Positive_regulation (accumulation) of FDG associated with hodgkin's disease
13) Confidence 0.39 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 1.08 Pain Relevance 0.16
PET/CT helps in the differential diagnosis by enabling the exact localization of increased FDG uptake [20,22,35,36].
Positive_regulation (increased) of FDG
14) Confidence 0.39 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 1.31 Pain Relevance 0.07
Patients responding to treatment had a significant reduction of tumor FDG accumulation in relation to those not responding [20,41,43-45].
Positive_regulation (accumulation) of FDG associated with cancer
15) Confidence 0.39 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 1.13 Pain Relevance 0
One limitation is cerebral metastasis, because the brain shows the highest normal FDG accumulation.
Positive_regulation (accumulation) of FDG in brain associated with metastasis
16) Confidence 0.39 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.98 Pain Relevance 0.07
Even though RT-induced inflammation accumulates 18F-FDG, there is data suggesting that a viable tumor shows higher uptake, thus making the differentiation feasible.
Positive_regulation (accumulates) of FDG associated with inflammation and cancer
17) Confidence 0.39 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 1.25 Pain Relevance 0.29
It is very interesting to mention that in the case of a low-grade lymphoma, an unexpected increase in FDG accumulation in any or all known parts of the disease during follow-up suggests transformation to a higher grade lymphoma [74-77].
Positive_regulation (accumulation) of FDG associated with lymphatic system cancer and disease
18) Confidence 0.39 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.91 Pain Relevance 0.13
This is consistent with the finding in our studies, suggesting that macrophages are responsible for the accumulation of FDG in atherosclerotic lesions.
Positive_regulation (accumulation) of FDG in macrophages associated with atherosclerosis
19) Confidence 0.39 Published 2006 Journal BMC Nucl Med Section Body Doc Link PMC1479805 Disease Relevance 0.77 Pain Relevance 0.17
Ogawa et al. [20] recently investigated the relationship between the accumulation of FDG and the pathologic characteristics of aortic atherosclerotic lesions in Watanabe heritable hyperlipidemic (WHHL) rabbits.
Positive_regulation (accumulation) of FDG associated with atherosclerosis
20) Confidence 0.39 Published 2006 Journal BMC Nucl Med Section Body Doc Link PMC1479805 Disease Relevance 0.55 Pain Relevance 0.11

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox