INT158828

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Context Info
Confidence 0.40
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (FAS) protein complex assembly (FAS) cytoplasm (FAS)
signal transducer activity (FAS) cytosol (FAS) signal transduction (FAS)
Anatomy Link Frequency
prefrontal 2
FAS (Homo sapiens)
Pain Link Frequency Relevance Heat
opiate 6 98.84 Very High Very High Very High
methadone 1 65.60 Quite High
addiction 2 52.08 Quite High
Disease Link Frequency Relevance Heat
Death 3 100.00 Very High Very High Very High
Apoptosis 3 88.24 High High
Opiate Addiction 2 52.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Phosphorylation of FADD (Fas-associated death domain protein) at serine 194 is increased in the prefrontal cortex of opiate abusers: relation to mitogen activated protein kinase, phosphoprotein enriched in astrocytes of 15 kDa, and Akt signaling pathways involved in neuroplasticity.
Positive_regulation (increased) of Phosphorylation (Phosphorylation) of Fas in prefrontal associated with opiate and death
1) Confidence 0.40 Published 2009 Journal Neuroscience Section Title Doc Link 19303913 Disease Relevance 0.58 Pain Relevance 0.33

General Comments

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