INT158990

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.78
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 2.48
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PAPPA) peptidase activity (PAPPA) extracellular region (PAPPA)
Anatomy Link Frequency
plaques 1
PAPPA (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 104 71.80 Quite High
metalloproteinase 15 70.16 Quite High
Inflammation 59 67.52 Quite High
cytokine 7 66.16 Quite High
ischemia 72 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
Bioavailability 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Catecholamine 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerotic Plaque 30 99.84 Very High Very High Very High
Acute Coronary Syndrome 211 98.84 Very High Very High Very High
Ectopic Pregnancy 95 98.00 Very High Very High Very High
Necrosis 69 94.96 High High
Death 64 88.32 High High
Myocardial Infarction 123 72.12 Quite High
Angina 104 71.80 Quite High
INFLAMMATION 63 67.52 Quite High
Hypoxia 11 60.88 Quite High
Pathologic Processes 3 48.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The kinetics of PAPP-A release and the corresponding optimal sampling protocols in ACS remain to be determined (Quin QP et al. 2002).
Localization (release) of PAPP-A associated with acute coronary syndrome
1) Confidence 0.78 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.58 Pain Relevance 0.07
RESULTS: Subjects with PAPP-A concentrations in the highest tertile were at higher risk for death (HR > 2.00; p < or = 0.05 at 2 years) even after adjusting for cTnI at presentation.
Localization (presentation) of PAPP-A
2) Confidence 0.73 Published 2009 Journal Clin. Biochem. Section Body Doc Link 19328196 Disease Relevance 0 Pain Relevance 0
As a consequence, they concluded that serum concentrations of placental markers such as PAPP-A, HLP, and LIF could not be used to differentiate EP from abnormal IUP.12

VEGF

Localization (markers) of PAPP-A associated with ectopic pregnancy
3) Confidence 0.73 Published 2008 Journal Clinics Section Body Doc Link PMC2664731 Disease Relevance 0.44 Pain Relevance 0.03
It is difficult to measure PAPP-A present in atherosclerotic plaques by immunoassays because they are designed to detect PAPP-A present in pregnancy sera.
Localization (present) of PAPP-A in plaques associated with atherosclerotic plaque
4) Confidence 0.73 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.60 Pain Relevance 0.06
However the overall correlation of PAPP-A with Catnip and CK-MB concentrations appears to be weak, indicating that increased PAPP-A cannot be attributed to myocardial necrosis.
Localization (correlation) of PAPP-A associated with necrosis
5) Confidence 0.73 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.86 Pain Relevance 0.11

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox