INT15900

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Context Info
Confidence 0.61
First Reported 1987
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 7
Disease Relevance 2.57
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (PEBP1) mitochondrion (PEBP1) extracellular space (PEBP1)
aging (PEBP1) Golgi apparatus (PEBP1) cytoplasm (PEBP1)
Anatomy Link Frequency
hippocampus 1
PEBP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Hippocampus 8 97.64 Very High Very High Very High
Opioid 2 97.28 Very High Very High Very High
anesthesia 4 65.20 Quite High
Enkephalin 1 48.84 Quite Low
Neuropeptide 6 25.00 Low Low
Disease Link Frequency Relevance Heat
Benign Prostatic Hypertrophy 4 100.00 Very High Very High Very High
Ovarian Cancer 111 99.80 Very High Very High Very High
Pressure And Volume Under Development 54 99.32 Very High Very High Very High
Learning Disorders 2 99.06 Very High Very High Very High
Bardet-biedl Syndrome 21 88.24 High High
Apoptosis 12 80.92 Quite High
Cancer 75 78.56 Quite High
Urethral Obstruction 1 75.00 Quite High
Death 3 70.04 Quite High
Stress Incontinence 1 38.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The distribution and localization of HCNP-related components and the expression of their mRNAs support the notion that the precursor protein is multifunctional.
Gene_expression (expression) of HCNP
1) Confidence 0.61 Published 2000 Journal Prog. Neurobiol. Section Abstract Doc Link 10622376 Disease Relevance 0.06 Pain Relevance 0.22
Furthermore, several lines of evidence obtained from studies of humans and animal models suggest that certain types of memory and learning disorders are associated with abnormal accumulation and expression of HCNP analogue peptide and/or its precursor protein mRNA in the hippocampus.
Gene_expression (expression) of HCNP in hippocampus associated with learning disorders and hippocampus
2) Confidence 0.55 Published 2000 Journal Prog. Neurobiol. Section Abstract Doc Link 10622376 Disease Relevance 0.10 Pain Relevance 0.15
PEBP1 was detected in 29 out of 30 ascites samples and discriminated ovarian cancer sera from controls (p = 0.02).
Gene_expression (detected) of PEBP1 associated with pressure and volume under development and ovarian cancer
3) Confidence 0.55 Published 2008 Journal J Transl Med Section Abstract Doc Link PMC2503970 Disease Relevance 0.50 Pain Relevance 0
Independent evidence for ovarian cancer-specific expression of PEBP1 in patient sera was found by ELISA assays and antibody arrays with anti-PEBP1 antibodies.
Gene_expression (expression) of PEBP1 associated with ovarian cancer
4) Confidence 0.55 Published 2008 Journal J Transl Med Section Abstract Doc Link PMC2503970 Disease Relevance 0.49 Pain Relevance 0
Benign prostatic hypertrophy (BPH) produces symptoms that currently can only be treated surgically either by open or endoscopic prostatectomy.
Gene_expression (produces) of Benign prostatic hypertrophy associated with benign prostatic hypertrophy
5) Confidence 0.28 Published 1987 Journal Rofo Section Abstract Doc Link 2446357 Disease Relevance 0.35 Pain Relevance 0.07
In conclusion, using a novel type of biotinylated recombinant antibodies that we call biobodies, we identified complement catabolitic products, EMILIN2, Von Willebrand factor and PEBP1 or a related protein, as candidate markers for ovarian carcinoma.


Gene_expression (products) of PEBP1 associated with ovarian cancer
6) Confidence 0.24 Published 2008 Journal J Transl Med Section Body Doc Link PMC2503970 Disease Relevance 1.06 Pain Relevance 0
Inhibition of protein kinase-A by overexpression of the cloned human protein kinase inhibitor.
Gene_expression (overexpression) of kinase inhibitor
7) Confidence 0.03 Published 1991 Journal Mol. Endocrinol. Section Title Doc Link 1770951 Disease Relevance 0 Pain Relevance 0

General Comments

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