INT159009

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2010
Negated 1
Speculated 1
Reported most in Title
Documents 2
Total Number 3
Disease Relevance 2.00
Pain Relevance 1.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Il6st) extracellular space (Il6st) cellular_component (Il6st)
Anatomy Link Frequency
sciatic nerve 1
dorsal root ganglia 1
Il6st (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 25 99.84 Very High Very High Very High
Inflammation 30 99.48 Very High Very High Very High
Sciatic nerve 4 99.18 Very High Very High Very High
Arthritis 51 98.32 Very High Very High Very High
cytokine 6 95.96 Very High Very High Very High
Peripheral nerve injury 4 95.52 Very High Very High Very High
Neuropathic pain 4 95.12 Very High Very High Very High
nociceptor 2 84.72 Quite High
Hyperalgesia 18 44.48 Quite Low
antinociception 3 8.84 Low Low
Disease Link Frequency Relevance Heat
Pain 22 99.84 Very High Very High Very High
INFLAMMATION 27 99.48 Very High Very High Very High
Experimental Arthritis 1 98.84 Very High Very High Very High
Injury 2 96.72 Very High Very High Very High
Arthritis 59 95.40 Very High Very High Very High
Neuropathic Pain 4 95.12 Very High Very High Very High
Nervous System Injury 6 95.08 Very High Very High Very High
Pressure And Volume Under Development 12 58.92 Quite High
Hyperalgesia 19 44.48 Quite Low
Arthralgia 3 23.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Bilateral changes in IL-6 protein, but not in its receptor gp130, in rat dorsal root ganglia following sciatic nerve ligature.
Neg (not) Regulation (changes) of gp130 in dorsal root ganglia associated with sciatic nerve
1) Confidence 0.18 Published 2009 Journal Cell. Mol. Neurobiol. Section Title Doc Link 19330444 Disease Relevance 0.34 Pain Relevance 0.31
We used sciatic nerve ligature (ScNL) to investigate temporal changes in IL-6 and its receptor gp130 in both ipsilateral and contralateral lumbal (L4-L5) dorsal root ganglia (DRG).
Spec (investigate) Regulation (changes) of gp130 in sciatic nerve associated with sciatic nerve
2) Confidence 0.18 Published 2009 Journal Cell. Mol. Neurobiol. Section Abstract Doc Link 19330444 Disease Relevance 0.28 Pain Relevance 0.28
Differential effects of locally and systemically administered soluble glycoprotein 130 on pain and inflammation in experimental arthritis

Introduction

Regulation (effects) of soluble glycoprotein 130 associated with pain, inflammation, experimental arthritis and arthritis
3) Confidence 0.05 Published 2010 Journal Arthritis Res Ther Section Title Doc Link PMC2945031 Disease Relevance 1.38 Pain Relevance 0.83

General Comments

This test has worked.

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