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Context Info
Confidence 0.62
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Fgf1) cytoplasm (Fgf1) cytosol (Fgf1)
extracellular space (Fgf1) extracellular region (Fgf1) proteinaceous extracellular matrix (Fgf1)
Anatomy Link Frequency
limb 1
Fgf1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 6 98.00 Very High Very High Very High
Restless leg syndrome 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Toxicity 1 98.66 Very High Very High Very High
Cv Unclassified Under Development 6 98.00 Very High Very High Very High
Increased Venous Pressure Under Development 3 83.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In phase I and phase II clinical trials, NV1FGF effectively reduced the number of amputations and deaths in the trials, with minimal toxicity, and in conjunction with a sustained increase in mRNA and protein levels of FGF1 and its receptors in patients with critical limb ischemia (CLI).
Transcription (levels) of FGF1 in limb associated with toxicity and ischemia
1) Confidence 0.62 Published 2009 Journal Curr Opin Investig Drugs Section Abstract Doc Link 19333884 Disease Relevance 0.71 Pain Relevance 0.41

General Comments

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