INT159096

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.14
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 0.20
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CNGB3) transport (CNGB3)
CNGB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 99.64 Very High Very High Very High
Lasting pain 4 98.16 Very High Very High Very High
Disease Link Frequency Relevance Heat
Pain 4 98.16 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3).
Negative_regulation (inhibitors) of channel-3
1) Confidence 0.14 Published 2009 Journal Bioorg. Med. Chem. Lett. Section Title Doc Link 19553111 Disease Relevance 0 Pain Relevance 0.09
A series of indole amidines modified at the 2-position of the indole ring were evaluated as inhibitors of Acid-Sensing Ion Channel-3 (ASIC3), a novel target for the treatment of chronic pain.
Negative_regulation (inhibitors) of Channel-3 associated with lasting pain
2) Confidence 0.12 Published 2009 Journal Bioorg. Med. Chem. Lett. Section Abstract Doc Link 19553111 Disease Relevance 0.10 Pain Relevance 0.10
A series of amiloride derivatives modified at the 5-position of the pyrazine ring were evaluated as inhibitors of acid-sensing ion channel-3 (ASIC3), a novel target for the treatment of chronic pain.
Negative_regulation (inhibitors) of channel-3 associated with lasting pain
3) Confidence 0.10 Published 2009 Journal Bioorg. Med. Chem. Lett. Section Abstract Doc Link 19339181 Disease Relevance 0.10 Pain Relevance 0.10
Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3).
Negative_regulation (inhibitors) of channel-3 associated with pain
4) Confidence 0.10 Published 2009 Journal Bioorg. Med. Chem. Lett. Section Title Doc Link 19339181 Disease Relevance 0 Pain Relevance 0.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox