INT159117

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Context Info
Confidence 0.56
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.50
Pain Relevance 2.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Gnb2l1) cytoskeleton (Gnb2l1) nucleus (Gnb2l1)
cell cycle (Gnb2l1) cytoplasm (Gnb2l1)
Anatomy Link Frequency
hippocampus 3
prefrontal 1
Gnb2l1 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 19 99.76 Very High Very High Very High
Hippocampus 16 99.60 Very High Very High Very High
Nucleus accumbens 3 94.32 High High
Pyramidal cell 2 86.56 High High
addiction 6 70.36 Quite High
opiate 2 42.96 Quite Low
Neuropeptide 4 25.00 Low Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 3 92.28 High High
Drug Dependence 4 70.36 Quite High
Opiate Addiction 2 43.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings suggest that morphine reward can influence the expression of RACK1 in mouse hippocampus and prefrontal cortex through regulating CREB transcription.
Regulation (influence) of Gene_expression (expression) of RACK1 in hippocampus associated with hippocampus and morphine
1) Confidence 0.56 Published 2009 Journal Neuroscience Section Abstract Doc Link 19341783 Disease Relevance 0.13 Pain Relevance 0.84
The purpose of this study is to investigate the effect of overexpression of RACK1 on the conditioned place preference (CPP) and the level of p-ERK in morphine reexposure mice.
Spec (investigate) Regulation (effect) of Gene_expression (overexpression) of RACK1 associated with morphine
2) Confidence 0.27 Published 2009 Journal Arch Ital Biol Section Abstract Doc Link 20162862 Disease Relevance 0.24 Pain Relevance 0.68
These findings suggest that morphine reward can influence the expression of RACK1 in mouse hippocampus and prefrontal cortex through regulating CREB transcription.
Regulation (influence) of in prefrontal Gene_expression (expression) of RACK1 in hippocampus associated with hippocampus and morphine
3) Confidence 0.19 Published 2009 Journal Neuroscience Section Abstract Doc Link 19341783 Disease Relevance 0.13 Pain Relevance 0.84

General Comments

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