INT159120

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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.37
Pain Relevance 1.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Gnb2l1) cytoskeleton (Gnb2l1) nucleus (Gnb2l1)
cell cycle (Gnb2l1) cytoplasm (Gnb2l1)
Anatomy Link Frequency
dentate gyrus 1
hippocampus 1
Gnb2l1 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 10 98.68 Very High Very High Very High
Hippocampus 14 98.56 Very High Very High Very High
Pyramidal cell 2 95.04 Very High Very High Very High
addiction 6 90.32 High High
opiate 2 62.92 Quite High
Neuropeptide 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Drug Dependence 4 90.32 High High
Opiate Addiction 2 63.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of RACK1 and CREB protein was negative in CA1, CA3 and DG of hippocampus.
Protein_catabolism (protein) of RACK1 in hippocampus associated with hippocampus
1) Confidence 0.26 Published 2009 Journal Neuroscience Section Abstract Doc Link 19341783 Disease Relevance 0.14 Pain Relevance 0.86
The expression of RACK1 and CREB protein was strongly positive in CA1, CA3 and dentate gyrus (DG) of the hippocampus of morphine-treated mice brain, especially the pyramidal neurons in the DG of the hippocampus.
Protein_catabolism (protein) of RACK1 in dentate gyrus associated with pyramidal cell, hippocampus and morphine
2) Confidence 0.26 Published 2009 Journal Neuroscience Section Abstract Doc Link 19341783 Disease Relevance 0.23 Pain Relevance 0.92

General Comments

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