INT15915

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Context Info
Confidence 0.41
First Reported 1991
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.44
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SGCG) cytoskeleton (SGCG) cytoskeleton organization (SGCG)
cytoplasm (SGCG)
Anatomy Link Frequency
muscle 2
SGCG (Homo sapiens)
Pain Link Frequency Relevance Heat
Botox 1 100.00 Very High Very High Very High
Pain 1 87.36 High High
agonist 2 84.56 Quite High
Dopamine 1 84.24 Quite High
antagonist 1 58.24 Quite High
Angina 2 49.44 Quite Low
opiate 1 42.64 Quite Low
Disease Link Frequency Relevance Heat
Spasticity 1 99.96 Very High Very High Very High
Cerebral Palsy 2 97.80 Very High Very High Very High
Pain 1 87.36 High High
Left Ventricular Dysfunction 3 75.00 Quite High
Angina 1 49.44 Quite Low
Coronary Artery Disease 2 36.64 Quite Low
Cv General 3 Under Development 1 34.56 Quite Low
Arrhythmias 2 Under Development 1 33.76 Quite Low
Contracture 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We next investigated whether beta gamma subunits play a role in the sensitization of type VI adenylyl cyclase activity; using expression of alpha tau to inhibit beta gamma-mediated effects, we found that the quinpirole-induced sensitization of type VI adenylyl cyclase was abolished.
Negative_regulation (abolished) of Positive_regulation (sensitization) of type
1) Confidence 0.41 Published 1996 Journal Mol. Pharmacol. Section Abstract Doc Link 8622641 Disease Relevance 0 Pain Relevance 0.14
Intramuscular injections of botulinum toxin type A (BTX-A) have increasingly been used to reduce spasticity in specific muscle groups in children with cerebral palsy.
Negative_regulation (reduce) of Positive_regulation (injections) of type in muscle associated with spasticity, cerebral palsy and botox
2) Confidence 0.41 Published 2001 Journal J. Neurol. Section Abstract Doc Link 11357236 Disease Relevance 0.36 Pain Relevance 0.14
In type B, the ejection fraction initially increased but decreased in late exercise.
Negative_regulation (decreased) of Positive_regulation (increased) of type
3) Confidence 0.32 Published 1991 Journal Eur J Cardiothorac Surg Section Abstract Doc Link 1772676 Disease Relevance 0.07 Pain Relevance 0

General Comments

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