INT159186

Context Info Confidence 0.49 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.25 Pain Relevance 1.40

cytosol (DYNLL1) transport (DYNLL1) mitochondrion (DYNLL1) plasma membrane (DYNLL1) cytoskeleton (DYNLL1) nucleus (DYNLL1)

Anatomy Link Frequency PPC 2 DYNLL1 (Homo sapiens)

Pain Link Frequency Relevance Heat Pain 3 99.72 Pin-prick hyperalgesia 3 99.56 magnetoencephalography 3 90.56 Hyperalgesia 10 84.48 c fibre 1 77.52 central sensitization 1 55.72 Peripheral sensitization 1 49.48 Inflammation 1 47.36 nociceptor 1 25.00

Disease Link Frequency Relevance Heat Pain 3 99.72 Hyperalgesia 14 99.56 Injury 1 51.56 Nervous System Injury 1 48.00 INFLAMMATION 1 47.36

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

During pin-prick hyperalgesia significantly higher activation was detected in contralateral PPC and bilateral S2 but not in S1 compared to normal pin-prick pain.

Positive_regulation (activation) of Neg (not) Gene_expression (detected) of pin in PPC associated with pain, hyperalgesia and pin-prick hyperalgesia

1) Confidence 0.49 Published 2010 Journal Eur J Pain Section Abstract Doc Link 19346142 Disease Relevance 1.25 Pain Relevance 1.40

General Comments

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