INT159303

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Context Info
Confidence 0.44
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.96
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (NGF) signal transduction (NGF) extracellular space (NGF)
extracellular region (NGF)
Anatomy Link Frequency
nociceptors 2
NGF (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 3 100.00 Very High Very High Very High
Analgesic 6 99.02 Very High Very High Very High
nociceptor 3 96.80 Very High Very High Very High
Lasting pain 2 95.76 Very High Very High Very High
agonist 4 92.32 High High
qutenza 1 86.64 High High
Pain 5 84.60 Quite High
Spinal cord 1 83.92 Quite High
Cannabinoid 4 75.00 Quite High
Cannabinoid receptor 1 74.32 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 100.00 Very High Very High Very High
Pain 5 95.76 Very High Very High Very High
Neuropathic Pain 1 95.24 Very High Very High Very High
Demyelinating Disease 1 71.92 Quite High
Disease 2 70.80 Quite High
Obesity 1 69.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To explain the mechanism at the basis of this analgesic effect different hypotheses have been proposed: effect on inflammatory cells, reduction of basal NGF tone, induction of beta-endorphin release from keratinocytes, direct action on nociceptors.
Regulation (effect) of Negative_regulation (reduction) of NGF in nociceptors associated with inflammation, nociceptor and analgesic
1) Confidence 0.44 Published 2009 Journal J. Soc. Biol. Section Abstract Doc Link 19358815 Disease Relevance 0.96 Pain Relevance 1.39

General Comments

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