INT159386

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (TRPV1) aging (Calca) intracellular (Calca)
cytoplasm (Calca) lipid metabolic process (TRPV1) cytosol (TRPV1)
Anatomy Link Frequency
sensory neurons 3
TRPV1 (Homo sapiens)
Calca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 5 100.00 Very High Very High Very High
Analgesic 1 100.00 Very High Very High Very High
Inflammation 1 94.12 High High
Pain 1 93.60 High High
central sensitization 1 89.72 High High
Lasting pain 2 88.68 High High
medulla 1 81.88 Quite High
antagonist 1 78.92 Quite High
qutenza 2 67.32 Quite High
Disease Link Frequency Relevance Heat
Nociception 3 95.88 Very High Very High Very High
INFLAMMATION 1 94.12 High High
Pain 3 93.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of TRPV1 mediates calcitonin gene-related peptide release, which excites trigeminal sensory neurons and is attenuated by a retargeted botulinum toxin with anti-nociceptive potential.
Positive_regulation (Activation) of TRPV1 in sensory neurons Positive_regulation (mediates) of Localization (release) of calcitonin gene-related peptide in sensory neurons associated with nociception, analgesic and calcitonin gene-related peptide
1) Confidence 0.05 Published 2009 Journal J. Neurosci. Section Title Doc Link 19369567 Disease Relevance 0.44 Pain Relevance 0.69

General Comments

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