INT159432

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Context Info
Confidence 0.16
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 5.00
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
liver 1
hs (Mus musculus)
Pain Link Frequency Relevance Heat
tetrodotoxin 1 92.36 High High
conotoxin 1 91.68 High High
Inflammation 31 82.64 Quite High
cytokine 20 50.00 Quite Low
Inflammatory response 2 41.56 Quite Low
Pain 8 25.56 Quite Low
tolerance 24 18.96 Low Low
ischemia 2 6.32 Low Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 368 100.00 Very High Very High Very High
Insulin Resistance 100 98.72 Very High Very High Very High
Hyperinsulinism 4 98.72 Very High Very High Very High
Diabetes Mellitus 44 95.52 Very High Very High Very High
Sepsis 12 85.56 High High
Hypertrophy 4 85.56 High High
Injury 4 83.52 Quite High
INFLAMMATION 32 82.64 Quite High
Heat Stress Disorders 4 82.52 Quite High
Infection 2 74.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Animals and in vivo HS+MES treatment
Gene_expression (treatment) of HS associated with shock
1) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 0.46 Pain Relevance 0
Interestingly, HS+MES treatment enhanced the insulin-stimulated IR?
Gene_expression (treatment) of HS associated with shock
2) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 1.11 Pain Relevance 0
In addition to the increased insulin signaling in the liver with HS+MES treatment, we observed that HS+MES affected the levels of serum TNF-?
Gene_expression (affected) of HS in liver associated with shock and hyperinsulinism
3) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 1.32 Pain Relevance 0
HS was produced by infrared rays, and low-intensity direct electrical current was delivered through insulated electrodes.
Gene_expression (produced) of HS associated with shock
4) Confidence 0.15 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 1.13 Pain Relevance 0
The myosin light chain phosphatase (MLCP) inhibitor calyculin-A reduced the NaHS-induced relaxation, but the Rho-kinase inhibitor Y-27632 had no influence.
Gene_expression (reduced) of NaHS
5) Confidence 0.06 Published 2009 Journal Eur. J. Pharmacol. Section Abstract Doc Link 19374871 Disease Relevance 0 Pain Relevance 0.14
HS is found ubiquitously expressed on cell surfaces and in extracellular compartments.
Gene_expression (expressed) of HS
6) Confidence 0.01 Published 2008 Journal Crit Care Section Body Doc Link PMC2575560 Disease Relevance 0.98 Pain Relevance 0.13

General Comments

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