INT159437

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Context Info
Confidence 0.50
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.04
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lung 1
mast cell 1
seb (Mus musculus)
Pain Link Frequency Relevance Heat
isoflurane 10 96.56 Very High Very High Very High
anesthesia 10 95.68 Very High Very High Very High
substance P 2 94.76 High High
antagonist 24 92.16 High High
Inflammation 124 90.80 High High
5HT 1 89.68 High High
Neuropeptide 4 87.76 High High
adenocard 72 85.04 High High
agonist 42 82.72 Quite High
qutenza 2 72.28 Quite High
Disease Link Frequency Relevance Heat
Infection 28 99.58 Very High Very High Very High
Toxicity 12 98.84 Very High Very High Very High
Death 64 91.68 High High
Lung Injury 70 91.28 High High
INFLAMMATION 102 90.80 High High
Hypoxia 132 83.16 Quite High
Apoptosis 37 82.92 Quite High
Body Weight 14 74.64 Quite High
Stress 1 71.00 Quite High
Unconsciousness 2 68.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this model of polymicrobial lung infection, intratracheal (IT) injection of both lipopolysaccharide (LPS) and staphylococcal enterotoxin B (SEB) strongly potentiates their toxicity [13].
Localization (injection) of SEB in lung associated with toxicity and infection
1) Confidence 0.50 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1088279 Disease Relevance 1.44 Pain Relevance 0.44
IT administration of LPS and SEB.
Localization (administration) of SEB
2) Confidence 0.44 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1088279 Disease Relevance 0.75 Pain Relevance 0.30
Moreover, clearance of Staphylococcus Enterotoxin B (SEB)-activated TCR V?
Localization (clearance) of SEB
3) Confidence 0.43 Published 2008 Journal Immunity Section Body Doc Link PMC2270348 Disease Relevance 0.84 Pain Relevance 0.03
In addition, SEA (but not SEB) significantly released mast cell TNF-alpha.
Localization (released) of SEB in mast cell
4) Confidence 0.11 Published 2009 Journal Eur. J. Pharmacol. Section Abstract Doc Link 19375418 Disease Relevance 0 Pain Relevance 0.41

General Comments

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