INT159455

Context Info Confidence 0.00 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.84 Pain Relevance 0.57

mitochondrion (Vamp1) vesicle-mediated transport (Vamp1)

Anatomy Link Frequency brain 2 Vamp1 (Mus musculus) Ppidl1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Substantia nigra 2 90.36 Nucleus accumbens 2 84.16 Morphine 4 82.92 addiction 4 75.20 opiate 2 36.32

Disease Link Frequency Relevance Heat Sprains And Strains 12 76.72 Drug Dependence 2 75.20 Opiate Addiction 2 5.00

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Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In most brain regions there was a decrease in D1-like binding in LEW rats after self-administration while the F344 animals displayed an increment.

LEW Binding (binding) of D1-like in brain

1) Confidence 0.00 Published 2009 Journal Neuropharmacology Section Abstract Doc Link 19376142 Disease Relevance 0.42 Pain Relevance 0.28

In most brain regions there was a decrease in D1-like binding in LEW rats after self-administration while the F344 animals displayed an increment.

LEW Binding (binding) of D1-like in brain

2) Confidence 0.00 Published 2009 Journal Neuropharmacology Section Abstract Doc Link 19376142 Disease Relevance 0.42 Pain Relevance 0.28

General Comments

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