INT159493

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.18
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

CDAN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Crohn's disease 36 100.00 Very High Very High Very High
Adalimumab 33 80.80 Quite High
Infliximab 72 74.64 Quite High
abdominal pain 6 62.56 Quite High
antagonist 2 61.92 Quite High
Inflammation 20 50.00 Quite Low
methotrexate 5 48.16 Quite Low
corticosteroid 17 12.96 Low Low
Etanercept 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 162 100.00 Very High Very High Very High
Pancreatitis 5 100.00 Very High Very High Very High
Inflammatory Bowel Disease 66 93.28 High High
Nicotine Addiction 4 86.12 High High
Congenital Anomalies 1 76.00 Quite High
Ulcers 2 66.40 Quite High
Diarrhoea 1 63.08 Quite High
Abdominal Pain 6 62.56 Quite High
Hepatotoxicity 1 50.88 Quite High
Recurrence 12 42.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This report supports the concept of an association between idiopathic pancreatitis and CD, based on a significant and close relation between the levels of serum amylase and lipase, and CDAI.
CDAI Binding (association) of associated with crohn's disease and pancreatitis
1) Confidence 0.36 Published 2009 Journal Korean J Gastroenterol Section Abstract Doc Link 19381059 Disease Relevance 0.98 Pain Relevance 0.28
In most clinical trials exploring biological therapies in CD, efficacy has been evaluated using the CrohnÂ’s Disease Activity Index (CDAI), a score that combines both clinical and laboratory parameters, where clinical remission is defined as a CDAI ?
CDAI Binding (using) of associated with disease
2) Confidence 0.18 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012434 Disease Relevance 0.55 Pain Relevance 0.30
For CD patients, in the multivariate analysis, once adjusted for sex, age, duration of disease, number of previous admissions, previous surgery, presence of perianal disease and concomitant treatment at the beginning, only the CDAI and the use of steroids were associated with the basal IBDQ score.
CDAI Binding (associated) of associated with crohn's disease and disease
3) Confidence 0.04 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2846867 Disease Relevance 0.65 Pain Relevance 0.05

General Comments

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