INT159548

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nfkbia) plasma membrane (Nfkbia) nucleus (Nfkbia)
enzyme binding (Nfkbia) protein complex (Nfkbia) cytoplasm (Nfkbia)
Nfkbia (Mus musculus)
Pain Link Frequency Relevance Heat
Hyperalgesia 5 97.56 Very High Very High Very High
Sciatic nerve 1 88.24 High High
agonist 3 84.40 Quite High
IPN 1 77.76 Quite High
Inflammation 3 73.52 Quite High
Intracerebroventricular 1 67.60 Quite High
Central nervous system 3 59.92 Quite High
Analgesic 4 56.80 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hyperalgesia 6 97.56 Very High Very High Very High
INFLAMMATION 3 73.52 Quite High
Inflammatory Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PEA prevented IkB-alpha degradation and p65 NF-kappaB nuclear translocation, confirming the involvement of this transcriptional factor in the control of peripheral hyperalgesia.
Regulation (involvement) of Protein_catabolism (degradation) of IkB-alpha associated with hyperalgesia
1) Confidence 0.18 Published 2009 Journal Eur. J. Pharmacol. Section Abstract Doc Link 19386271 Disease Relevance 0.62 Pain Relevance 0.82

General Comments

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