INT159616

Context Info Confidence 0.31 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.74 Pain Relevance 0.13

transport (Trpm1) plasma membrane (Trpm1) molecular_function (Trpm1) cellular_component (Trpm1) transmembrane transport (Trpm1)

Trpm1 (Mus musculus)

Pain Link Frequency Relevance Heat member 8 2 63.28

Disease Link Frequency Relevance Heat Melanoma 8 99.56 Skin Cancer 4 98.88 Nevus 8 98.16 Metastasis 1 70.40 Cancer 1 67.76

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Regional loss of the TRPM1 mRNA expression by a significant subset of dermal tumor cells or a complete absence of TRPM1 expression by the dermal tumor was identified in 27 of 33 (82%) nodular melanomas, but only 1 of 95 (1%) Spitz nevi.

Negative_regulation (loss) of Transcription (expression) of TRPM1 associated with melanoma, nevus and skin cancer

1) Confidence 0.31 Published 2009 Journal Mod. Pathol. Section Abstract Doc Link 19396153 Disease Relevance 1.74 Pain Relevance 0.13

General Comments

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