INT159657

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.65
Pain Relevance 1.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (NGF) signal transduction (NGF) extracellular space (NGF)
extracellular region (NGF)
Anatomy Link Frequency
annulus 1
nucleus pulposus 1
INSRR (Homo sapiens)
NGF (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 30 100.00 Very High Very High Very High
Stimulus evoked pain 4 87.48 High High
central pain 4 84.88 Quite High
Inflammation 16 76.64 Quite High
Facet joint 8 75.00 Quite High
Pain 10 66.00 Quite High
central sensitization 2 63.04 Quite High
cytokine 8 30.00 Quite Low
Lasting pain 6 25.00 Low Low
nociceptor 4 25.00 Low Low
Disease Link Frequency Relevance Heat
Hypersensitivity 4 87.48 High High
Inflammatory Pain 4 86.80 High High
Pain 20 84.88 Quite High
Nociception 12 83.84 Quite High
INFLAMMATION 16 76.64 Quite High
Disease 4 67.08 Quite High
Hyperalgesia 2 65.44 Quite High
Intervertebral Disk Displacement 4 37.28 Quite Low
Ganglion Cysts 2 8.72 Low Low
Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The analysis of these specimens revealed the presence of the neurotrophin (NGF) and its own receptor (TrkA) in all cases: the immunohistochemical reaction between the specimens and the specific antibodies marked with FITC was seen under fluoromicroscopy, but in none of the control cases treated with FITC only.
own receptor Binding (presence) of NGF
1) Confidence 0.00 Published 2009 Journal Eur Spine J Section Abstract Doc Link 19399531 Disease Relevance 0.34 Pain Relevance 0.26
The analysis of these specimens revealed the presence of the neurotrophin (NGF) and its own receptor (TrkA) in all cases: the immunohistochemical reaction between the specimens and the specific antibodies marked with FITC was seen under fluoromicroscopy, but in none of the control cases treated with FITC only.
own receptor Binding (presence) of NGF
2) Confidence 0.00 Published 2009 Journal Eur Spine J Section Abstract Doc Link 19399531 Disease Relevance 0.34 Pain Relevance 0.26
Gigante and colleagues recently reported the presence of nerve growth factor (NGF) mRNA, the high-affinity tyrosine kinase A receptor and the low-affinity p75 receptor in rounded cells in the disc annulus and nucleus pulposus [5].
receptor Binding (presence) of nerve growth factor in nucleus pulposus associated with nerve growth factor
3) Confidence 0.00 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575628 Disease Relevance 0.49 Pain Relevance 0.48
Gigante and colleagues recently reported the presence of nerve growth factor (NGF) mRNA, the high-affinity tyrosine kinase A receptor and the low-affinity p75 receptor in rounded cells in the disc annulus and nucleus pulposus [5].
receptor Binding (presence) of nerve growth factor in annulus associated with nerve growth factor
4) Confidence 0.00 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575628 Disease Relevance 0.49 Pain Relevance 0.48

General Comments

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