INT159782

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Context Info
Confidence 0.79
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.51
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Tnf) signal transduction (Tnf) extracellular space (Tnf)
extracellular region (Tnf) plasma membrane (Tnf) intracellular (Tnf)
Tnf (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 10 93.60 High High
pain pelvic 1 78.52 Quite High
endometriosis 2 77.76 Quite High
cytokine 9 75.00 Quite High
metalloproteinase 11 50.00 Quite Low
Inflammation 11 20.16 Low Low
aspirin 1 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute Coronary Syndrome 17 98.96 Very High Very High Very High
Stable Angina Pectoris 10 93.60 High High
Hypertension 2 85.76 High High
Nicotine Addiction 2 84.92 Quite High
Endometriosis 4 84.16 Quite High
Obesity 3 84.00 Quite High
Reprotox - General 3 2 79.16 Quite High
Necrosis 2 50.00 Quite Low
Cancer 2 50.00 Quite Low
Increased Venous Pressure Under Development 9 37.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The correlation between TLR4 and TNF-?
Phosphorylation (correlation) of TNF
1) Confidence 0.79 Published 2010 Journal Clinical Medicine Insights. Cardiology Section Body Doc Link PMC2956475 Disease Relevance 1.11 Pain Relevance 0.17
By transfection of TAK1 siRNA, TNFalpha-induced phosphorylation of IkappaBalpha, JNK1/2, and p38MAPK, as well as IL-6 or IL-8 expression, were repressed.
Phosphorylation (phosphorylation) of TNFalpha
2) Confidence 0.19 Published 2009 Journal Mol. Cell. Endocrinol. Section Abstract Doc Link 19410630 Disease Relevance 0.39 Pain Relevance 0.19

General Comments

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