INT159794

Context Info Confidence 0.01 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.42 Pain Relevance 0.19

mitochondrion (Mapk9) intracellular (Tnf) extracellular matrix organization (Tnf) cytoplasm (Mapk9) cytosol (Mapk9) cell proliferation (Tnf)

Tnf (Mus musculus) Mapk9 (Mus musculus)

Pain Link Frequency Relevance Heat pain pelvic 1 84.92 endometriosis 2 84.16 cytokine 2 75.00

Disease Link Frequency Relevance Heat Endometriosis 4 90.56 Reprotox - General 3 2 85.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Using the NF-kappaB pathway array, we found that TNFalpha upregulated ICAM-3, IL-6, IL-8, TAK1, JNK2, RelA, and TLR4 expressions.

TNFalpha Positive_regulation (upregulated) of JNK2

1) Confidence 0.01 Published 2009 Journal Mol. Cell. Endocrinol. Section Abstract Doc Link 19410630 Disease Relevance 0.42 Pain Relevance 0.19

General Comments

This test has worked.