INT159837

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Context Info
Confidence 0.10
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.92
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) nucleolus (Fos) nucleus (Fos)
intracellular (Trim2) DNA binding (Fos) transcription factor binding (Fos)
Anatomy Link Frequency
spinal 2
Trim2 (Rattus norvegicus)
Fos (Rattus norvegicus)
Pain Link Frequency Relevance Heat
allodynia 1 99.28 Very High Very High Very High
Inflammation 4 98.88 Very High Very High Very High
Antinociceptive 1 95.80 Very High Very High Very High
narcan 1 91.44 High High
antagonist 1 91.08 High High
opioid receptor 2 90.64 High High
Pain 7 90.40 High High
antinociception 1 89.20 High High
COX2 1 88.08 High High
withdrawal 1 72.00 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 1 99.28 Very High Very High Very High
INFLAMMATION 2 98.88 Very High Very High Very High
Pain 3 90.40 High High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

10 85.96 High High
Nociception 3 84.84 Quite High
Colitis 5 83.28 Quite High
Dyspepsia 1 55.16 Quite High
Functional Bowel Disorder 1 50.92 Quite High
Enteropathy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this setting,NO2-Arg-Trim but not trimebutine, significantly down-regulated the spinal cFOS mRNA expression and increased blood concentrations of NO2 +NO3.
NO2-Arg-Trim Neg (not) Negative_regulation (down-regulated) of Transcription (expression) of cFOS in spinal
1) Confidence 0.10 Published 2009 Journal Pharmacol. Res. Section Abstract Doc Link 19416632 Disease Relevance 1.23 Pain Relevance 1.22

General Comments

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