INT159965

Context Info Confidence 0.00 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.49 Pain Relevance 0

intracellular (Gtf3a, TNF) extracellular matrix organization (TNF) DNA binding (Gtf3a) extracellular space (TNF) signal transduction (TNF) extracellular region (TNF)

Gtf3a (Rattus norvegicus) TNF (Homo sapiens)

Pain Link Frequency Relevance Heat Central nervous system 4 25.00 cytokine 2 25.00 Neuropathic pain 1 25.00

Disease Link Frequency Relevance Heat Necrosis 2 99.98 Cancer 2 99.80 Glioma 3 75.00 Stress 1 64.24 Increased Venous Pressure Under Development 2 26.08 Neuropathic Pain 1 25.00 Injury 1 25.00 Neurodegenerative Disease 1 25.00 Stroke 1 25.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Tumor necrosis factor (TNF)-alpha stimulated interleukin (IL)-6 release and induced the phosphorylation of myosin phosphatase targeting subunit (MYPT)-1, a Rho-kinase substrate.

factor Positive_regulation (stimulated) of Localization (release) of TNF associated with necrosis and cancer

1) Confidence 0.00 Published 2009 Journal Neurochem. Int. Section Abstract Doc Link 19427347 Disease Relevance 0.49 Pain Relevance 0

General Comments

This test has worked.