INT159968

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.61
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Tbca) nucleolus (Tbca) cytoskeleton (Tbca)
cytoplasm (Tbca)
Anatomy Link Frequency
spinal 1
endometrium 1
Tbca (Mus musculus)
Pain Link Frequency Relevance Heat
allodynia 1 97.32 Very High Very High Very High
Spinal cord 1 96.64 Very High Very High Very High
IPN 2 90.68 High High
spinal dorsal horn 2 90.40 High High
Inflammation 5 76.60 Quite High
nMDA receptor 2 75.00 Quite High
cva 1 72.88 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 1 97.32 Very High Very High Very High
Inflammatory Pain 2 90.68 High High
INFLAMMATION 3 76.60 Quite High
Hemorrhage 1 72.88 Quite High
Anaemia 1 70.24 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 51.84 Quite High
Leukemia 5 5.00 Very Low Very Low Very Low
Acute Myeloid Leukemia 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This observation pointed to the possibility that MEIS1 is an active cofactor of HOXA10 in the human endometrium.
Positive_regulation (active) of cofactor in endometrium
1) Confidence 0.04 Published 2008 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2387222 Disease Relevance 0.19 Pain Relevance 0.04
Inhibition of spinal NMDARs with D-APV completely eliminated the CFA-induced increase in NR1 immunoreactive density at synapses, and direct application of NMDA onto the spinal cord of naïve mice mimicked the effects of CFA, suggesting the importance of NMDARs activity in regulating the synaptic content of NR1 during inflammatory pain.
Positive_regulation (increase) of CFA-induced in spinal associated with ipn and spinal cord
2) Confidence 0.02 Published 2009 Journal Pain Section Abstract Doc Link 19427735 Disease Relevance 0.41 Pain Relevance 0.54

General Comments

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