INT159986

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.68
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.10
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Sptan1) plasma membrane (Sptan1) cytoskeleton (Sptan1)
protein complex (Sptan1) cytoplasm (Sptan1)
Anatomy Link Frequency
cleavage 2
lymphoblasts 2
Sptan1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 144 100.00 Very High Very High Very High
depression 1 98.96 Very High Very High Very High
Migraine 7 89.52 High High
headache 1 65.92 Quite High
nMDA receptor 6 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
excitatory amino acid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Migraine With Aura 4 100.00 Very High Very High Very High
Depression 1 98.96 Very High Very High Very High
Death 80 76.20 Quite High
Apoptosis 97 75.76 Quite High
Epstein-barr Virus 1 73.24 Quite High
Headache 6 69.76 Quite High
Neurodegenerative Disease 11 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low
Aging 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also verified that the expression of alpha-fodrin, which was 1 of the 15 genes that were differentially expressed in lymphoblasts originating from patients with MA, increased after cortical spreading depression in an animal model.
Positive_regulation (increased) of Gene_expression (expression) of alpha-fodrin in lymphoblasts associated with depression and migraine with aura
1) Confidence 0.68 Published 2009 Journal Neurosci. Res. Section Abstract Doc Link 19428688 Disease Relevance 0.79 Pain Relevance 0.65
-fodrin breakdown patterns produced by calpain or caspase-3, the effects of calpain and caspase inhibitors on glutamate-induced cleavage of ?
Positive_regulation (induced) of Gene_expression (produced) of fodrin in cleavage associated with glutamate
2) Confidence 0.30 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1526740 Disease Relevance 0.31 Pain Relevance 0.29

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox