INT160008

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Context Info
Confidence 0.49
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CDKN1B) endosome (CDKN1B) nucleoplasm (CDKN1B)
nucleus (CDKN1B) cell cycle (CDKN1B) kinase activity (CDKN1B)
CDKN1B (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 5 99.98 Very High Very High Very High
cINOD 11 91.84 High High
COX-2 inhibitor 1 78.88 Quite High
diclofenac 1 77.20 Quite High
acular 2 76.16 Quite High
Disease Link Frequency Relevance Heat
Necrosis 1 96.00 Very High Very High Very High
Apoptosis 6 95.48 Very High Very High Very High
Death 3 81.88 Quite High
INFLAMMATION 3 75.00 Quite High
Osteoporosis 1 64.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We further found that indomethacin, celecoxib and dexamethasone increased the mRNA and protein expressions of p27(kip1) and decreased those of cyclin D2 and p-cdk2 in hOBs.
Positive_regulation (increased) of Transcription (expressions) of kip1 associated with dexamethasone
1) Confidence 0.49 Published 2009 Journal Toxicology Section Abstract Doc Link 19428934 Disease Relevance 0.98 Pain Relevance 1.10

General Comments

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