INT160022

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Context Info
Confidence 0.53
First Reported 2009
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.75
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc12a2) plasma membrane (Slc12a2) transmembrane transport (Slc12a2)
Anatomy Link Frequency
tooth pulp 1
MDH 1
Slc12a2 (Mus musculus)
Pain Link Frequency Relevance Heat
Dorsal horn 4 98.96 Very High Very High Very High
Pain 5 98.52 Very High Very High Very High
Hyperalgesia 3 93.20 High High
GABAergic 2 90.56 High High
Central nervous system 2 86.96 High High
gABA 1 85.24 High High
Inflammation 8 79.92 Quite High
Face pain 2 75.00 Quite High
Spontaneous pain 1 68.80 Quite High
antinociception 1 66.56 Quite High
Disease Link Frequency Relevance Heat
Pain 3 98.52 Very High Very High Very High
Peripheral Arterial Disease 1 95.68 Very High Very High Very High
Hyperalgesia 3 93.20 High High
INFLAMMATION 5 79.92 Quite High
Facial Pain 2 75.00 Quite High
Hypersensitivity 1 36.96 Quite Low
Myelodysplastic Syndromes 2 5.00 Very Low Very Low Very Low
Ganglion Cysts 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we investigated the expression of KCC2 and NKCC1 mRNAs in mouse trigeminal subnucleus caudalis (Vc) after lipopolysaccharide (LPS) application to the tooth pulp by real-time reverse transcriptase-polymerase chain reaction (RT-PCR) method.
Spec (investigated) Transcription (expression) of NKCC1 in tooth pulp
1) Confidence 0.53 Published 2010 Journal Brain Res. Bull. Section Abstract Doc Link 20067823 Disease Relevance 0.35 Pain Relevance 0.43
In this study, we investigated the behavioral changes and the accompanying change in the expressions of KCC2 and NKCC1 mRNAs in mouse medullary dorsal horn (MDH) after subcutaneous injection of formalin into the left vibrissa pad.
Transcription (expressions) of NKCC1 in MDH associated with dorsal horn and peripheral arterial disease
2) Confidence 0.50 Published 2009 Journal Neurosci. Lett. Section Abstract Doc Link 19429157 Disease Relevance 0.41 Pain Relevance 0.46
As shown in Fig. 6 A, NKCC1 mRNA transcript was expressed in VNOs as well as the MOE, which was confirmed by sequencing.
Transcription (expressed) of NKCC1
3) Confidence 0.44 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2806418 Disease Relevance 0 Pain Relevance 0.09

General Comments

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