INT160048

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Context Info
Confidence 0.28
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (INPPL1, AKT1) cytoplasm (INPPL1, AKT1) cytosol (INPPL1, AKT1)
cell differentiation (AKT1) nucleoplasm (AKT1) transport (AKT1)
INPPL1 (Homo sapiens)
AKT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 6 96.60 Very High Very High Very High
Disease Link Frequency Relevance Heat
Reprotox - General 1 1 98.72 Very High Very High Very High
Cancer 4 93.52 High High
Disease 1 87.16 High High
INFLAMMATION 2 84.32 Quite High
Targeted Disruption 1 42.24 Quite Low
Colon Cancer 1 37.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The prostate cancer cell line LNCaP, lacking both critical enzymes in the negative control of PKB/Akt activation, PTEN and SHIP2, was the most sensitive to these effects, as assessed by analysing the cell cycle profile and expression of cell cycle regulating proteins.
SHIP2 Regulation (control) of Gene_expression (activation) of PKB/Akt associated with reprotox - general 1
1) Confidence 0.28 Published 2009 Journal Biochem. Pharmacol. Section Abstract Doc Link 19433066 Disease Relevance 0.60 Pain Relevance 0.42

General Comments

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