INT160060

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Context Info
Confidence 0.10
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.61

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Syt17 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bradykinin 3 100.00 Very High Very High Very High
antagonist 3 99.78 Very High Very High Very High
Calcium channel 1 99.56 Very High Very High Very High
sodium channel 2 98.66 Very High Very High Very High
tetrodotoxin 1 98.20 Very High Very High Very High
b2 receptor 1 97.68 Very High Very High Very High
Neuropeptide 2 86.24 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To further understand the mechanisms of the scorpion toxin action on NPY release, the effects of icatibant (HOE 140, a selective bradykinin-B2 receptor antagonist), tetrodotoxin (TTX, a sodium channel antagonist) and diltiazem (a calcium channel antagonist), and the effect of the scorpion toxin on bradykinin (BK, a potent vasorelaxant peptide of the kinin group) release were studied in both tissues.
Regulation (effect) of Localization (release) of BK associated with tetrodotoxin, calcium channel, antagonist, sodium channel, b2 receptor and bradykinin
1) Confidence 0.10 Published 2009 Journal Peptides Section Abstract Doc Link 19433126 Disease Relevance 0 Pain Relevance 0.61

General Comments

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