INT160091

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Context Info
Confidence 0.59
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.63
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (L1CAM) cell death (L1CAM) cell adhesion (L1CAM)
plasma membrane (L1CAM)
L1CAM (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 2 99.78 Very High Very High Very High
Disease Link Frequency Relevance Heat
Pancreatitis 2 99.78 Very High Very High Very High
Fibrosis 2 98.32 Very High Very High Very High
Adenocarcinoma 14 96.64 Very High Very High Very High
Malignant Neoplastic Disease 6 94.60 High High
Adhesions 2 86.24 High High
Pancreatic Cancer 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, Slug interacted with the L1CAM promoter, and its knockdown abrogated the TGF-beta1- and PMF-induced L1CAM expression.
Negative_regulation (abrogated) of Gene_expression (expression) of L1CAM
1) Confidence 0.59 Published 2009 Journal Cancer Res. Section Abstract Doc Link 19435915 Disease Relevance 0.68 Pain Relevance 0.07
Immunohistochemistry of tissues from chronic pancreatitis specimens revealed considerable L1CAM expression in ductal structures surrounded by dense fibrotic tissue, whereas no L1CAM staining was seen in normal pancreatic tissues.
Negative_regulation (revealed) of Gene_expression (expression) of L1CAM associated with fibrosis and chronic pancreatitis
2) Confidence 0.43 Published 2009 Journal Cancer Res. Section Abstract Doc Link 19435915 Disease Relevance 0.95 Pain Relevance 0.10

General Comments

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