INT160169

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Context Info
Confidence 0.75
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 9
Disease Relevance 8.67
Pain Relevance 7.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pde9a)
Anatomy Link Frequency
trigeminal ganglion 1
Aorta 1
middle cerebral artery 1
meninges 1
mesenteric artery 1
Pde9a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 54 100.00 Very High Very High Very High
trigeminal ganglion 45 98.28 Very High Very High Very High
Migraine 36 91.96 High High
headache 18 86.28 High High
Trigeminal neuralgia 9 83.92 Quite High
Disease Link Frequency Relevance Heat
Pain 45 98.96 Very High Very High Very High
Ganglion Cysts 45 98.28 Very High Very High Very High
Headache 54 91.96 High High
Trigeminal Autonomic Cephalalgias 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Aorta and mesenteric artery as well as cerebral neocortex and cerebellar cortex also showed expression of PDE9A, PDE10A and PDE11A.
Gene_expression (expression) of PDE9A in mesenteric artery
1) Confidence 0.75 Published 2009 Journal Brain Res. Section Abstract Doc Link 19445908 Disease Relevance 0.97 Pain Relevance 0.98
PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system.
Gene_expression (expression) of PDE9A associated with pain
2) Confidence 0.75 Published 2009 Journal Brain Res. Section Title Doc Link 19445908 Disease Relevance 0.98 Pain Relevance 0.93
Real-time PCR and Western blotting showed that PDE9A, PDE10A and PDE11A are expressed in components of the rat trigeminovascular pain signalling system including middle cerebral artery, basilar artery, meninges, trigeminal ganglion and spinal trigeminal nucleus.
Gene_expression (expressed) of PDE9A in spinal trigeminal nucleus associated with ganglion cysts, pain and trigeminal ganglion
3) Confidence 0.75 Published 2009 Journal Brain Res. Section Abstract Doc Link 19445908 Disease Relevance 1.00 Pain Relevance 0.80
We here present, for the first time, the expression of PDE9A, PDE10A, and PDE11A in the trigeminovascular system.
Gene_expression (expression) of PDE9A
4) Confidence 0.75 Published 2009 Journal Brain Res. Section Abstract Doc Link 19445908 Disease Relevance 0.77 Pain Relevance 0.86
Real-time PCR and Western blotting showed that PDE9A, PDE10A and PDE11A are expressed in components of the rat trigeminovascular pain signalling system including middle cerebral artery, basilar artery, meninges, trigeminal ganglion and spinal trigeminal nucleus.
Gene_expression (expressed) of PDE9A in trigeminal ganglion associated with ganglion cysts, pain and trigeminal ganglion
5) Confidence 0.25 Published 2009 Journal Brain Res. Section Abstract Doc Link 19445908 Disease Relevance 1.00 Pain Relevance 0.80
Real-time PCR and Western blotting showed that PDE9A, PDE10A and PDE11A are expressed in components of the rat trigeminovascular pain signalling system including middle cerebral artery, basilar artery, meninges, trigeminal ganglion and spinal trigeminal nucleus.
Gene_expression (expressed) of PDE9A in basilar artery associated with ganglion cysts, pain and trigeminal ganglion
6) Confidence 0.25 Published 2009 Journal Brain Res. Section Abstract Doc Link 19445908 Disease Relevance 1.00 Pain Relevance 0.80
Aorta and mesenteric artery as well as cerebral neocortex and cerebellar cortex also showed expression of PDE9A, PDE10A and PDE11A.
Gene_expression (expression) of PDE9A in Aorta
7) Confidence 0.25 Published 2009 Journal Brain Res. Section Abstract Doc Link 19445908 Disease Relevance 0.97 Pain Relevance 0.98
Real-time PCR and Western blotting showed that PDE9A, PDE10A and PDE11A are expressed in components of the rat trigeminovascular pain signalling system including middle cerebral artery, basilar artery, meninges, trigeminal ganglion and spinal trigeminal nucleus.
Gene_expression (expressed) of PDE9A in middle cerebral artery associated with ganglion cysts, pain and trigeminal ganglion
8) Confidence 0.25 Published 2009 Journal Brain Res. Section Abstract Doc Link 19445908 Disease Relevance 1.00 Pain Relevance 0.80
Real-time PCR and Western blotting showed that PDE9A, PDE10A and PDE11A are expressed in components of the rat trigeminovascular pain signalling system including middle cerebral artery, basilar artery, meninges, trigeminal ganglion and spinal trigeminal nucleus.
Gene_expression (expressed) of PDE9A in meninges associated with ganglion cysts, pain and trigeminal ganglion
9) Confidence 0.25 Published 2009 Journal Brain Res. Section Abstract Doc Link 19445908 Disease Relevance 1.00 Pain Relevance 0.80

General Comments

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