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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

response to stress (Prkcc, Src) cytoplasm (Prkcc, Src) cytosol (Prkcc, Src)
nucleus (Prkcc, Src) plasma membrane (Prkcc, Src) kinase activity (Prkcc, Src)
Prkcc (Mus musculus)
Src (Rattus norvegicus)
Pain Link Frequency Relevance Heat
mu opioid receptor 4 97.12 Very High Very High Very High
tolerance 1 86.88 High High
Analgesic 1 85.52 High High
Morphine 2 83.84 Quite High
opioid receptor 1 75.00 Quite High
Glutamate 1 59.24 Quite High
nMDA receptor 1 53.40 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This MOR-triggered signaling pathway recruits PKCgamma and Galphai subunits to activate Src tyrosine kinase, resulting in the potentiation of NMDAR function.
PKCgamma Positive_regulation (activate) of Src
1) Confidence 0.02 Published 2009 Journal Cell. Signal. Section Abstract Doc Link 19446022 Disease Relevance 0 Pain Relevance 0.51

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