INT16024

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Context Info
Confidence 0.60
First Reported 1991
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 2.74
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Cand1) nucleus (Cand1)
Anatomy Link Frequency
dorsal horn 1
Cand1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hyperalgesia 1 99.88 Very High Very High Very High
allodynia 1 99.54 Very High Very High Very High
spinal dorsal horn 3 99.36 Very High Very High Very High
Opioid 1 96.56 Very High Very High Very High
Thermal hyperalgesia 2 92.04 High High
Dorsal horn 2 88.44 High High
Neuropathic pain 4 85.76 High High
Dorsal horn neuron 1 75.00 Quite High
Sciatic nerve 1 74.60 Quite High
Peripheral nerve injury 1 59.32 Quite High
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 100 100.00 Very High Very High Very High
Hyperalgesia 3 99.88 Very High Very High Very High
Hyperlipidemia 48 99.58 Very High Very High Very High
Neuropathic Pain 5 99.54 Very High Very High Very High
Metabolic Syndrome 17 98.32 Very High Very High Very High
Diabetes Mellitus 70 97.68 Very High Very High Very High
Hyperglycemia 2 96.72 Very High Very High Very High
Hypertension 9 96.00 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

18 90.44 High High
Nervous System Injury 1 59.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Those encoding the major secretory proteins, protein B/C and protein D/E, are directly regulated by testicular androgen.
Regulation (regulated) of C and
1) Confidence 0.60 Published 1991 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 1785782 Disease Relevance 0 Pain Relevance 0.10
In combined hypercholesterolemia subgroups serum HDL-C and VLDL-C levels were not significantly affected by any of the treatments, whereas serum LDL-C level was significantly decreased by quinazolinones treatment, compared to either bezafibrate or their reference group (Table 3).
Neg (not) Regulation (affected) of C and associated with hyperlipidemia and disorder of lipid metabolism
2) Confidence 0.60 Published 2005 Journal Lipids Health Dis Section Body Doc Link PMC1266394 Disease Relevance 0.79 Pain Relevance 0
These data revealed a close association between the expression and loss of allodynia and hyperalgesia with changes in the levels of Homer1b/c and Shank1a in the spinal dorsal horn.
Regulation (changes) of c and in dorsal horn associated with hyperalgesia, allodynia and spinal dorsal horn
3) Confidence 0.44 Published 2005 Journal Neurosci. Lett. Section Abstract Doc Link 16002212 Disease Relevance 0.62 Pain Relevance 0.95
None of the foregoing treatments significantly affected serum triacylglycerol, HDL-C and VLDL-C levels.
Regulation (affected) of C and associated with disorder of lipid metabolism
4) Confidence 0.26 Published 2005 Journal Lipids Health Dis Section Body Doc Link PMC1266394 Disease Relevance 0.45 Pain Relevance 0
Pitavastatin produces adequate control of LDL-C and TG, along with potent and incremental HDL-C elevation, with a low frequency of DDIs.



Regulation (control) of C and associated with disorder of lipid metabolism
5) Confidence 0.26 Published 2009 Journal Vascular Health and Risk Management Section Abstract Doc Link PMC2788597 Disease Relevance 0.72 Pain Relevance 0

General Comments

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