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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Msr1) extracellular region (Col11a1) cell adhesion (Col11a1)
proteinaceous extracellular matrix (Col11a1) structural molecule activity (Col11a1) plasma membrane (Msr1)
Anatomy Link Frequency
Msr1 (Mus musculus)
Col11a1 (Mus musculus)
Crygs (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 2 97.88 Very High Very High Very High
Cannabinoid 1 94.20 High High
agonist 1 84.08 Quite High
antagonist 2 81.72 Quite High
Cannabinoid receptor 1 81.28 Quite High
Opioid 2 75.00 Quite High
MU agonist 1 75.00 Quite High
narcan 3 47.36 Quite Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 100.00 Very High Very High Very High
Bordatella Infection 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using the ligand-stimulated [(35)S]guanosine 5'-3-O-(thio)triphosphate (GTPgammaS) assay, we have found that 10 microM SR141716 slightly but significantly decreases the basal [(35)S]GTPgammaS binding in membranes of the wild-type and CB(1) receptor knockout mouse cortex, parental Chinese hamster ovary (CHO) cells, and CHO cells stably transfected with micro-opioid receptors, MOR-CHO.
SR141716 Negative_regulation (decreases) of CHO Binding (binding) of GTPgammaS in CHO associated with targeted disruption and opioid receptor
1) Confidence 0.00 Published 2009 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 19448142 Disease Relevance 0.17 Pain Relevance 0.41

General Comments

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