INT160413

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Context Info
Confidence 0.50
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cd40lg) extracellular space (Cd40lg) mitochondrion (Tat)
extracellular region (Cd40lg) plasma membrane (Cd40lg) biosynthetic process (Tat)
Tat (Mus musculus)
Cd40lg (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 1 100.00 Very High Very High Very High
Morphine 6 99.20 Very High Very High Very High
antagonist 1 87.60 High High
opioid receptor 1 87.16 High High
chemokine 1 84.92 Quite High
Opioid 1 73.16 Quite High
Inflammation 1 68.08 Quite High
opiate 1 59.44 Quite High
Disease Link Frequency Relevance Heat
Cancer 1 100.00 Very High Very High Very High
Necrosis 1 100.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 7 91.12 High High
INFLAMMATION 1 68.08 Quite High
Viral Meningitis 1 66.08 Quite High
Syndrome 1 62.72 Quite High
Immunodeficiency 1 62.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the mRNA expression of inducible nitric oxide synthase (iNOS), CD40 ligand, Interferon-gamma-inducible protein 10 (IP-10), and the proinflammatory cytokines tumor necrosis factor alpha (TNFalpha), interleukin (IL)-1beta, and IL-6, which were elevated with Tat alone, were dramatically enhanced with Tat in the presence of morphine.
Tat Positive_regulation (enhanced) of Gene_expression (expression) of CD40 ligand associated with necrosis, cancer, morphine and cytokine
1) Confidence 0.50 Published 2009 Journal J. Neurovirol. Section Abstract Doc Link 19462331 Disease Relevance 0.98 Pain Relevance 0.86

General Comments

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