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Context Info
Confidence 0.24
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.21
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Icam5)
Anatomy Link Frequency
leukocyte 1
molar 1
Icam5 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 45 80.12 Quite High
Pain 2 74.76 Quite High
Inflammation 13 73.20 Quite High
headache 2 73.20 Quite High
Sciatic nerve 1 50.00 Quite Low
local anesthetic 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 8 100.00 Very High Very High Very High
Dengue 64 99.98 Very High Very High Very High
Infection 23 99.64 Very High Very High Very High
Dengue Hemorrhagic Fever 31 92.68 High High
Autoimmune Disease 6 88.84 High High
Apoptosis 8 87.92 High High
Hemorrhage 3 85.28 High High
Viral Meningitis 3 82.28 Quite High
Leukopenia 1 80.52 Quite High
Disease 15 75.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dengue binds to Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin (DC-SIGN).
Intercellular adhesion molecule-3 Binding (binds) of associated with dengue and adhesions
1) Confidence 0.24 Published 2009 Journal Virol J Section Abstract Doc Link PMC2789730 Disease Relevance 2.58 Pain Relevance 0.17
The intracellular adhesion molecules (ICAMs), ICAM-1, ICAM-2 and ICAM-3, are cell surface ligands for leukocyte integrins.
ICAM-3 Binding (ligands) of in leukocyte associated with adhesions
2) Confidence 0.03 Published 2010 Journal Immune Network Section Body Doc Link PMC2881426 Disease Relevance 0.64 Pain Relevance 0.23
S50-R50HPb-CD and S75-R25HPb-CD complexes have decreased onset (p < 0.01 and p < 0.05, respectively), without changing motor block intensity (Emax) as compared to plain drugs; ii) sensory block evaluation has revealed higher analgesic intensity with S50-R50HPb-CD (2-fold, p < 0.001) and S75-R25HPb-CD (1.5-1.8-fold, p < 0.01 and p < 0.001, respectively) with both molar ratios (1:1 and 1:2, LA:CD), in addition to prolonging analgesic effect as compared to S50-R50 and S75-R25.
S50-R50HPb-CD Binding (complexes) of in molar
3) Confidence 0.02 Published 2005 Journal Rev Bras Anestesiol Section Body Doc Link 19471836 Disease Relevance 0 Pain Relevance 0

General Comments

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