INT160556

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Context Info
Confidence 0.60
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 7
Disease Relevance 2.94
Pain Relevance 1.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
blood 1
sympathetic 1
TNS3 (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal-cord stimulation 68 99.84 Very High Very High Very High
tolerance 5 96.80 Very High Very High Very High
Spinal cord 8 85.16 High High
Pain 24 81.44 Quite High
painful pain 4 72.04 Quite High
Visceral pain 4 69.04 Quite High
medulla 4 62.80 Quite High
Pain threshold 3 50.00 Quite Low
palliative 1 28.48 Quite Low
ischemia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 39 100.00 Very High Very High Very High
Dyspnea 112 99.32 Very High Very High Very High
Colon Cancer 21 95.64 Very High Very High Very High
Complex Regional Pain Syndromes 8 81.84 Quite High
Coronary Heart Disease 4 80.36 Quite High
Pain 18 79.64 Quite High
Nociception 4 72.04 Quite High
Dizziness 4 70.12 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

4 69.04 Quite High
Adenocarcinoma 1 54.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since the sympathetic effects as shown by SCS must be indirect effects of the electrical stimulation, we postulate that TENS produces these effects in the same way.
Gene_expression (produces) of TENS in sympathetic associated with spinal-cord stimulation
1) Confidence 0.60 Published 2010 Journal Acta Neurochir (Wien) Section Body Doc Link PMC2901492 Disease Relevance 0.37 Pain Relevance 0.78
TENS produced no significant effect on BP, regardless of intensity.
Neg (no) Gene_expression (produced) of TENS
2) Confidence 0.59 Published 2009 Journal Clin J Pain Section Body Doc Link 19851157 Disease Relevance 0.12 Pain Relevance 0
RESULTS: Significant increases in negative peak latency and mechanical pain threshold over time (p = 0.015, 0.002) were found within the 2 active TENS groups.
Gene_expression (groups) of TENS
3) Confidence 0.58 Published 2009 Journal J Rehabil Med Section Body Doc Link 19479152 Disease Relevance 0.15 Pain Relevance 0
The fall in MCA blood flow velocity as a result of hyperventilation was a little less prominent when TENS was applied, but this did not reach statistical significance.
Gene_expression (applied) of TENS in blood associated with dyspnea
4) Confidence 0.52 Published 2010 Journal Acta Neurochir (Wien) Section Body Doc Link PMC2901492 Disease Relevance 0.39 Pain Relevance 0
For HR and MAP, too, the effects of different TENS frequencies did not differ (P?
Gene_expression (frequencies) of TENS
5) Confidence 0.52 Published 2010 Journal Acta Neurochir (Wien) Section Body Doc Link PMC2901492 Disease Relevance 0.22 Pain Relevance 0
Some of the effects seen in SCS can be produced by TENS as well.
Gene_expression (produced) of TENS associated with spinal-cord stimulation
6) Confidence 0.52 Published 2010 Journal Acta Neurochir (Wien) Section Body Doc Link PMC2901492 Disease Relevance 0.51 Pain Relevance 0.99
These ten miRNAs were chosen based on their high expression levels in tumors displaying p53 deletion, their relationship with p53 and their predicted target mRNAs (e.g. cytochrome C, ECIP-1, MAPPKKK1, TEM6, E2F5, GATA6, PP2B, and eIF5A).
Gene_expression (expression) of TEM6 associated with cancer
7) Confidence 0.14 Published 2006 Journal Biomark Insights Section Body Doc Link PMC2134920 Disease Relevance 1.06 Pain Relevance 0

General Comments

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