INT16068

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Context Info
Confidence 0.60
First Reported 1983
Last Reported 2010
Negated 4
Speculated 3
Reported most in Abstract
Documents 27
Total Number 30
Disease Relevance 20.51
Pain Relevance 6.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SERPINB1) cytoplasm (SERPINB1)
Anatomy Link Frequency
blood 1
coronary artery 1
face 1
tubule 1
T-cell 1
SERPINB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antinociception 9 100.00 Very High Very High Very High
substance P 6 99.34 Very High Very High Very High
Crohn's disease 9 99.24 Very High Very High Very High
Neuritis 5 99.10 Very High Very High Very High
Lasting pain 1 98.52 Very High Very High Very High
rheumatoid arthritis 68 98.48 Very High Very High Very High
Sicca syndrome 2 98.00 Very High Very High Very High
Morphine 2 97.68 Very High Very High Very High
spinal inflammation 20 97.52 Very High Very High Very High
Pain 14 96.64 Very High Very High Very High
Disease Link Frequency Relevance Heat
Leptospirosis 42 100.00 Very High Very High Very High
Hepatitis 22 99.90 Very High Very High Very High
Pancreatitis 6 99.64 Very High Very High Very High
Stroke 14 99.46 Very High Very High Very High
Autoimmune Disease 59 99.40 Very High Very High Very High
Disease 251 99.24 Very High Very High Very High
Experimental Autoimmune Neuritis 5 99.10 Very High Very High Very High
Asymptomatic Infections 12 98.88 Very High Very High Very High
Cerebrovascular Disease 5 98.80 Very High Very High Very High
Sjoegrens Syndrome 8 98.54 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Anti-Trichinella IgG were detected in 10.0% (95% Cl 8.5-11.6%) of them.
Gene_expression (detected) of Anti-Trichinella IgG
1) Confidence 0.60 Published 2005 Journal Trans. R. Soc. Trop. Med. Hyg. Section Abstract Doc Link 15922379 Disease Relevance 0.20 Pain Relevance 0.07
Levels of anti-streptokinase antibodies were measured in 75 Indian patients who were divided into three groups.
Gene_expression (Levels) of anti-streptokinase
2) Confidence 0.53 Published 1991 Journal Int. J. Cardiol. Section Abstract Doc Link 1791089 Disease Relevance 0.25 Pain Relevance 0.08
There was no significant difference in the anti-streptokinase levels among the three groups.
Gene_expression (levels) of anti-streptokinase
3) Confidence 0.53 Published 1991 Journal Int. J. Cardiol. Section Abstract Doc Link 1791089 Disease Relevance 0.34 Pain Relevance 0.09
Rheumatoid factor, anti-nuclear antibody, anti-Ro, and anti-La antibodies were examined for each of the patients.
Spec (examined) Gene_expression (examined) of anti-La
4) Confidence 0.29 Published 2007 Journal Clin. Rheumatol. Section Abstract Doc Link 16547690 Disease Relevance 1.51 Pain Relevance 0.58
Rheumatoid factor, anti-nuclear antibody, anti-Ro, and anti-La antibodies were examined for each of the patients.
Spec (examined) Gene_expression (examined) of anti-Ro
5) Confidence 0.29 Published 2007 Journal Clin. Rheumatol. Section Abstract Doc Link 16547690 Disease Relevance 1.52 Pain Relevance 0.58
The authors found temporal changes in the expression of five proteins (serpin B3, serpin B1, annexin A3, collagen ?
Gene_expression (expression) of serpin B1
6) Confidence 0.22 Published 2010 Journal Proteome Sci Section Body Doc Link PMC3016264 Disease Relevance 0.21 Pain Relevance 0.07
Double staining confocal microscope studies using anti-human protein-gene-product 9.5, anti-tubule, anti-neurofilament, and anti-synaptophysin antibodies were performed to assess specific accumulation within swellings.
Gene_expression (using) of anti-tubule in tubule
7) Confidence 0.13 Published 2003 Journal Neurology Section Body Doc Link 12963753 Disease Relevance 0.23 Pain Relevance 0
Of the 43 persons with IgM anti-Leptospira antibodies, only 17 (39.5%) reported having illness that met the WHO criteria for leptospirosis; the remaining 26 (60.5%) had asymptomatic infection.
Gene_expression (antibodies) of anti-Leptospira associated with asymptomatic infections and leptospirosis
8) Confidence 0.10 Published 2002 Journal Emerging Infectious Diseases Section Body Doc Link PMC2738501 Disease Relevance 1.14 Pain Relevance 0.11
Spontaneous coronary artery dissection presenting as an ischaemic stroke in a middle-aged man with anti-cardiolipin antibodies: a case report

Introduction

Gene_expression (antibodies) of anti-cardiolipin in coronary artery associated with stroke
9) Confidence 0.04 Published 2010 Journal J Med Case Reports Section Title Doc Link PMC2848682 Disease Relevance 0.83 Pain Relevance 0.11
Five new anti-glycan antibodies anti-chitobioside IgA (ACCA), anti-laminaribioside IgG (ALCA), anti-manobioside IgG (AMCA) and antibodies against chemically synthesized (?)
Gene_expression (synthesized) of anti-manobioside IgG
10) Confidence 0.04 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2827710 Disease Relevance 1.07 Pain Relevance 0.07
Anti-double stranded DNA, anti-Sjogrens Syndrome A, anti-Sjogrens Syndrome B and anti-ribonucleoprotein antibodies (anti-SSA, anti-SSB, anti-RNP), anti-Sm, anti-Scl-70, antineutrophil cytoplasmic antibodies, anticardiolipin antibodies, cryoglobulins, C3, C4, C-reactive protein, complete blood count, electrolytes, creatinine, hepatic transaminases, alkaline phosphatase and urinalysis were all normal or negative.
Neg (negative) Gene_expression (negative) of anti-Sm in blood associated with sjoegrens syndrome
11) Confidence 0.04 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2901265 Disease Relevance 0.50 Pain Relevance 0.11
Sera positive for ANA by indirect immunofluorescence were further analysed for the presence of anti-extractable nuclear antigens (anti-ENA) by Addressable Laser Bead Immunoassays (Menarini Diagnostics) in accordance with the manufacturer's instructions [28].
Spec (analysed) Gene_expression (presence) of anti-ENA
12) Confidence 0.04 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526573 Disease Relevance 0 Pain Relevance 0.09
Studies revealed that tripelennamine (Tp) alone produced antinociception (ANTI) in mice and also caused potentiation when combined with morphine (M) or nalbuphene (NB).
Gene_expression (produced) of ANTI associated with antinociception and morphine
13) Confidence 0.04 Published 1983 Journal Life Sci. Section Abstract Doc Link 6835002 Disease Relevance 0 Pain Relevance 1.16
Anti-ENA reactivity other than anti-SSA(Ro) was not detected.
Neg (not) Gene_expression (detected) of Anti-ENA
14) Confidence 0.03 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC416448 Disease Relevance 0.61 Pain Relevance 0.21
IgG anti-Sacc antibodies were detected in 63% (25/40) of CD patients, compared with 15% (4/27) of UC patients (p less than 0.001) and 8% (5/60) healthy adult controls (p less than 0.001).
Gene_expression (detected) of anti-Sacc associated with inflammatory bowel disease and crohn's disease
15) Confidence 0.02 Published 1990 Journal Int. Arch. Allergy Appl. Immunol. Section Abstract Doc Link 2246081 Disease Relevance 1.28 Pain Relevance 0.35
Using ELISA method, anti-H. pylori IgG and IgM were detected in 181 sera from patients (aged 2-14 years) complaining of repeated midepigastical pain and 152 sera of controls.
Gene_expression (detected) of anti-H associated with pain
16) Confidence 0.01 Published 1996 Journal Zhonghua Liu Xing Bing Xue Za Zhi Section Abstract Doc Link 8758417 Disease Relevance 0.42 Pain Relevance 0.10
The present results provide evidence that AEA is able to suppress anti-CD3/anti-CD28-induced T-cell proliferation mainly via CB2 receptors.
Gene_expression (proliferation) of anti-CD28-induced in T-cell
17) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2809084 Disease Relevance 0.81 Pain Relevance 0.47
Susceptibility to EAN in a rat F2 population segregated with high levels of anti-PNM IgG, as well as IgG2b and IgG2c isotype levels, which support that disease genes regulate preferential Th1/Th2 differentiation.
Gene_expression (levels) of anti-PNM IgG associated with disease and neuritis
18) Confidence 0.01 Published 2001 Journal J. Neuroimmunol. Section Abstract Doc Link 11585618 Disease Relevance 1.25 Pain Relevance 0.63
Mice immunized against anti-substance P (anti-SP) monoclonal antibodies produced anti-SP anti-idiotypic antibodies (SPAb2).
Gene_expression (produced) of anti-SP associated with substance p
19) Confidence 0.01 Published 1988 Journal Brain Res. Section Abstract Doc Link 2465066 Disease Relevance 0.13 Pain Relevance 0.30
The serum concentrations of autoantibodies were analyzed by ELISA according to the manufacturer's instructions: anti-Sjögren syndrome-associated antigen A antibodies, anti-Sjögren syndrome-associated antigen B antibodies, anti-Sm antibodies, anti-Sc170 antibodies, anti-dsDNA antibodies, anti-cardiolipin (anti-CL) antibodies (Cogent Diagnostic, Edinburgh, UK), and anti-U1RNP antibodies (Pharmacia and Upjohn, Freiburg, Germany).
Gene_expression (antibodies) of anti-cardiolipin associated with syndrome and sicca syndrome
20) Confidence 0.01 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911856 Disease Relevance 0.31 Pain Relevance 0.33

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