INT160753

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.27
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PNOC) extracellular region (PNOC)
Anatomy Link Frequency
amygdala 3
hippocampus 1
PNOC (Homo sapiens)
Pain Link Frequency Relevance Heat
Hippocampus 4 99.68 Very High Very High Very High
amygdala 8 99.04 Very High Very High Very High
alcohol 4 88.16 High High
agonist 2 74.88 Quite High
orphanin 12 72.40 Quite High
gABA 2 66.80 Quite High
GABAergic 2 64.36 Quite High
opiate 2 47.28 Quite Low
Neuropeptide 2 45.64 Quite Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 2 83.20 Quite High
Recurrence 4 53.88 Quite High
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We hypothesise that chronic ethanol intake downregulates PNOC and OPRL1 gene expression in the hippocampus and amygdala, respectively.
Negative_regulation (downregulates) of Gene_expression (expression) of PNOC in amygdala associated with hippocampus and amygdala
1) Confidence 0.36 Published 2009 Journal Brain Res. Section Abstract Doc Link 19501074 Disease Relevance 0.14 Pain Relevance 0.58
We hypothesise that chronic ethanol intake downregulates PNOC and OPRL1 gene expression in the hippocampus and amygdala, respectively.
Negative_regulation (downregulates) of in hippocampus Gene_expression (expression) of PNOC in amygdala associated with hippocampus and amygdala
2) Confidence 0.12 Published 2009 Journal Brain Res. Section Abstract Doc Link 19501074 Disease Relevance 0.14 Pain Relevance 0.58

General Comments

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