INT160760

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.31

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peptidase activity (Cma1) extracellular region (Cma1) intracellular (Cma1)
Anatomy Link Frequency
brain 1
Cma1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 1 95.48 Very High Very High Very High
Endogenous opioid 1 91.92 High High
Pain 1 90.64 High High
Opioid 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Anxiety Disorder 1 94.96 High High
Pain 1 90.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The purpose of the present study was to evaluate the neuroendocrine effect of chlormadinone acetate (CMA) administration, analyzing the brain content of allopregnanolone (ALLO), an endogenous neurosteroid gamma-aminobutyric acid agonist with anxiolytic properties, and the brain level of beta-endorphin (beta-END), an endogenous opioid implicated in pain mechanism, emotional state and autonomic control.
Regulation (effect) of CMA in brain associated with pain, anxiety disorder, endogenous opioid and agonist
1) Confidence 0.21 Published 2009 Journal Contraception Section Abstract Doc Link 19501216 Disease Relevance 0.19 Pain Relevance 0.31

General Comments

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