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Context Info
Confidence 0.40
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.57

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nucleoplasm (ATM) signal transduction (ATM) cell death (ATM)
cytoplasmic membrane-bounded vesicle (ATM) nucleus (ATM) DNA binding (ATM)
ATM (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 7 96.80 Very High Very High Very High
agonist 1 87.84 High High
Disease Link Frequency Relevance Heat
Apoptosis 6 100.00 Very High Very High Very High
Ataxia 1 100.00 Very High Very High Very High
Cancer 6 93.88 High High
Death 1 88.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These events were associated with rapid co-ordinated transcription of pro-apoptotic genes including Fas/CD95, Bcl-2 and caspase families and ataxia telangiectasia mutated (ATM)/CHK2/p53 DNA damage response pathway.
Transcription (transcription) of ATM associated with ataxia and apoptosis
1) Confidence 0.40 Published 2009 Journal Carcinogenesis Section Abstract Doc Link 19502594 Disease Relevance 1.03 Pain Relevance 0.57

General Comments

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