INT160829

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tyr, RYBP) nucleoplasm (RYBP) intracellular (RYBP)
DNA binding (RYBP) cell proliferation (Tyr) pigmentation (Tyr)
Anatomy Link Frequency
SK-MEL-28 1
Tyr (Mus musculus)
RYBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 10 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Toxicity 5 99.96 Very High Very High Very High
Skin Cancer 8 99.08 Very High Very High Very High
Cancer 4 75.00 Quite High
Cutaneous Melanoma 1 35.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the current study, we investigated further the role of tyrosinase in APAP toxicity in SK-MEL-28 melanoma cells in the presence of a short hairpin RNA (shRNA) plasmid, silencing tyrosinase gene.
tyrosinase Spec (investigated) Regulation (role) of APAP in SK-MEL-28 associated with toxicity, paracetamol and skin cancer
1) Confidence 0.04 Published 2009 Journal Int. J. Oncol. Section Abstract Doc Link 19513568 Disease Relevance 0.75 Pain Relevance 0.53

General Comments

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