INT160861

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Context Info
Confidence 0.49
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Erbb2, EGF) plasma membrane (Erbb2, EGF) extracellular space (EGF)
extracellular region (EGF) nucleus (Erbb2) kinase activity (Erbb2)
Erbb2 (Mus musculus)
EGF (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 1 49.04 Quite Low
Disease Link Frequency Relevance Heat
Cancer 5 98.04 Very High Very High Very High
Leukemia 1 94.52 High High
Toxicity 1 72.32 Quite High
Mucositis 2 54.48 Quite High
Vomiting 2 51.84 Quite High
Diarrhoea 1 50.16 Quite High
Abdominal Pain 1 49.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since the discovery of a role for HER2 and other EGF receptors in the development and progression of cancer, they have become targets for a number of targeted anti-cancer drugs.
HER2 Regulation (role) of EGF associated with cancer
1) Confidence 0.49 Published 2009 Journal Curr Drug Targets Section Abstract Doc Link 19519356 Disease Relevance 0.73 Pain Relevance 0

General Comments

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