INT160903

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Context Info
Confidence 0.22
First Reported 2005
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.69
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (SERPINF1) extracellular space (SERPINF1) aging (SERPINF1)
extracellular region (SERPINF1)
Anatomy Link Frequency
blood 1
endothelium 1
SERPINF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 2 84.16 Quite High
Glutamate 1 84.00 Quite High
Bioavailability 2 25.00 Low Low
Fibrositis 24 5.00 Very Low Very Low Very Low
Central nervous system 21 5.00 Very Low Very Low Very Low
Pain 13 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
cva 5 5.00 Very Low Very Low Very Low
spastic colon 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Fatigue Syndrome 184 99.76 Very High Very High Very High
Stress 15 98.28 Very High Very High Very High
Hypoxia 7 98.14 Very High Very High Very High
Disease 18 74.12 Quite High
Increased Venous Pressure Under Development 21 28.40 Quite Low
Syndrome 39 5.00 Very Low Very Low Very Low
Sleep Disorders 24 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 14 5.00 Very Low Very Low Very Low
Pain 14 5.00 Very Low Very Low Very Low
Cerebral Amyloid Angiopathy 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PEDF and C4 were significantly associated with CFS but not to gender (table 4).
PEDF Binding (associated) of associated with chronic fatigue syndrome
1) Confidence 0.22 Published 2005 Journal BMC Neurol Section Body Doc Link PMC1326206 Disease Relevance 1.17 Pain Relevance 0.04
The aim of this study was to assess in-vivo the effect of chronic hypoxic stress on endothelium-mediated vasodilator response of hindlimb vascular bed, especially as regards to endothelium-derived hyperpolarizing factor (EDHF) and nitric oxide (NO) pathway contribution.
endothelium-derived hyperpolarizing factor Binding (regards) of in endothelium associated with stress and hypoxia
2) Confidence 0.07 Published 2009 Journal Vascul. Pharmacol. Section Abstract Doc Link 19520187 Disease Relevance 0.44 Pain Relevance 0.08
Nitric oxide (NO) has potent vasodilator effects that interact with other local vasoactive mediators (eg, prostanoids, endothelin, and the endothelium-derived hyperpolarizing factor) and with neural inputs to determine overall vascular tone and blood flow (Moncada and Higgs 1993, 2006).
endothelium-derived hyperpolarizing factor Spec (determine) Binding (interact) of in blood
3) Confidence 0.02 Published 2009 Journal Trends in Cardiovascular Medicine Section Body Doc Link PMC2984617 Disease Relevance 0.07 Pain Relevance 0

General Comments

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