INT160961

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Context Info
Confidence 0.28
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.89
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Fth1) oxidoreductase activity (Fth1)
Anatomy Link Frequency
femur 1
Fth1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 7 98.66 Very High Very High Very High
Inflammation 57 88.56 High High
abdominal pain 6 87.12 High High
interstitial cystitis 1 79.92 Quite High
Pain 6 74.16 Quite High
palliative 1 70.44 Quite High
substance P 14 5.00 Very Low Very Low Very Low
Inflammatory stimuli 5 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Fibrous Histiocytoma 50 100.00 Very High Very High Very High
INFLAMMATION 69 98.48 Very High Very High Very High
Fever Of Unknown Origin 1 98.48 Very High Very High Very High
Metastasis 8 93.36 High High
Injury 13 91.40 High High
Cancer 49 91.24 High High
Malignant Neoplastic Disease 10 87.60 High High
Abdominal Pain 6 87.12 High High
Contusions 1 86.40 High High
Sarcoma 15 85.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results indicated that several genes known to be part of the inflammatory response were found downstream of PAR1 activation (b2m, ccl7, cd200, cd63, cdbpd, cfl1, dusp1, fkbp1a, fth1, hspb1, marcksl1, mmp2, myo5a, nfkbia, pax1, plaur, ppia, ptpn1, ptprcap, s100a10, sim2, and tnfaip2).
Gene_expression (cdbpd) of fth1 associated with inflammatory response
1) Confidence 0.28 Published 2007 Journal BMC Physiol Section Body Doc Link PMC1853107 Disease Relevance 0.86 Pain Relevance 0.34
We found the genes sparc, ednrb, junb, cdkn1a, bcl2, ccl5, abcc1 over-expressed and the genes sod1, s100a10 and fth1 under-expressed after inoculation of Tx2-6.
Gene_expression (expressed) of fth1
2) Confidence 0.23 Published 2009 Journal Toxicon Section Abstract Doc Link 19524607 Disease Relevance 0.07 Pain Relevance 0.07
Our case report shows that primary intra-abdominal MFH can present in unusual ways including high-grade fever of unknown origin.
Gene_expression (present) of MFH associated with fever of unknown origin and malignant fibrous histiocytoma
3) Confidence 0.16 Published 2006 Journal Int Semin Surg Oncol Section Body Doc Link PMC1513591 Disease Relevance 1.36 Pain Relevance 0.16
Bader et al. [16] reported a 14-year-old girl who underwent plate osteosynthesis because of supracondylar femur fracture. 10 months after metal removal, a refracture and detection of an MFH at the same location occured.
Gene_expression (detection) of MFH in femur associated with malignant fibrous histiocytoma
4) Confidence 0.13 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2889898 Disease Relevance 1.60 Pain Relevance 0.06

General Comments

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